Introduction: Objective: This study aimed to assess the possible variations in root canal anatomy and topography of the apices of first and second maxillary molars. Materials and methods: A total of 67 first and second maxillary permanent molars were collected. Access cavity was prepared and 2% methylene blue was injected. The teeth were demineralized by 5% nitric acid and cleared with met...

objective: knowledge about the internal anatomy of the root canal and apical foramen is a critical prerequisite for root canal therapy and is necessary for the success of endodontic treatment. this study aimed to determine the distance of apical foramen from the anatomical apex and apical constriction, evaluate the deviation of apical foramen from the anatomical apex and specify the most common...

introduction: objective: this study aimed to assess the possible variations in root canal anatomy and topography of the apices of first and second maxillary molars. materials and methods: a total of 67 first and second maxillary permanent molars were collected. access cavity was prepared and 2% methylene blue was injected. the teeth were demineralized by 5% nitric acid and cleared with methyl s...

Objectives Adequate knowledge about canal anatomy is necessary for clinicians to prevent any damage to the periodontium. The aim of this study was to evaluate the canal and apical complexities of the mandibular first and second premolars in an Iranian population. Methods One-hundred mandibular first (n=50) and second (n=50) premolars were collected. After access cavity preparation, 2% methylen...

AIM To evaluate the accuracy of the Root ZX, Elements-Diagnostic, Precision AL and Raypex 5 electronic apex locators when compared to radiographs for locating the apical constriction. METHODOLOGY The apical constriction of 693 canals in 245 maxillary and mandibular teeth was located in vivo with four electronic apex locators (EALs) and radiographically. After extraction the actual location of...

Apical constriction is an essential cell behavior during neural tube closure, but its underlying mechanisms are not fully understood. Lulu, or EPB4.1l5, is a FERM domain protein that has been implicated in apical constriction and actomyosin contractility in mouse embryos and cultured cells. Interference with the function of Lulu in Xenopus embryos by a specific antisense morpholino oligonucleot...

Apical constriction is a widely utilized cell shape change linked to folding, bending and invagination of polarized epithelia. It remains unclear how apical constriction is regulated spatiotemporally during tissue invagination and how this cellular process contributes to tube formation in different developmental contexts. Using Drosophila salivary gland (SG) invagination as a model, we show tha...

Apical constriction is a major mechanism underlying tissue internalization during development. This cell constriction typically requires actomyosin contractility. Thus, understanding apical constriction requires characterization of the mechanics and regulation of actomyosin assemblies. We have analyzed the relationship between myosin and the polarity regulators Par-6, aPKC and Bazooka (Par-3) (...

Apical constriction typically accompanies inward folding of an epithelial sheet. In recent years there has been progress in understanding mechanisms of apical constriction and their contribution to morphogenetic processes. Sea urchin embryos form a specialized region of ectoderm, the ciliary band, which is a strip of epithelium, three to five cells wide, encircling the oral ectoderm and functio...